Clean & Seal
A new non-surgical concept for mucositis treatment. Efficient, simple and biocompatible - now available at Unident!
The CLEAN&SEAL® concept, which was developed based on scientific data1, 2 provides guidance and support for the treatment and control of peri-implant mucositis. It allows clinicians to save implants and prevent the development of peri-implantitis, which helps to further prevent larger procedures required to rebuild peri-implant tissue.
Provides guidance and support for the treatment and control of peri-implant mucositis
Peri-implant disease is divided into two subgroups: peri-implant mucositis,1-3 which is characterized by soft tissue inflammation without bone loss and peri-implantitis, which is characterized by progressive loss of the supporting bone.4 If left untreated, in the worst-case peri-implantitis can result in the loss of the affected implant. This problem is relatively new to clinicians and dissatisfying for patients. It is of great importance to treat peri-implant disease at an early stage, with infection control and extensive debridement being crucial for positive treatment outcomes.1, 2 The likelihood of success is further increased by the supportive application of sealing agents for protection and regenerative support and by regular follow-up to monitor and control inflammation.6
EARLY AND EFFECTIVE INTERCEPTION OF PERI-IMPLANT DISEASE
PROVIDED BY DR MARISA RONCATI (ITALY)
Effects of Clean & Seal
1. ATTRACTS BLOOD
2. STABILIZES COAGULUM AND SUPPORTS TISSUE REGENERATION
3. BACTERIOSTATIC EFFECT PROVIDES PROTECTION
4. GROWTH FACTORS ATTRACTED BY HYALURONIC ACID
5. COORDINATES INFLAMMATION AND ACCELERATES ANGIOGENESIS
• SOFTENING OF THE EXTRACELLULAR MATRIX OF THE BIOFILM5
• ENHANCING BACTERIAL REMOVAL BY MECHANICAL DEBRIDEMENT
• ELIMINATION OF THE BIOFILM
HYADENT - TISSUE REGENERATOR
Each pack of HYADENT BG contains two cartridges, each filled with 1.2 ml of hyaluronic acid at a concentration of 1.8% (1.6% cross-linked, 0.2% natural hyaluronic acid). One cartridge contains sufficient hyalu-ronic acid for multiple application according to the proposed protocol.
- Speeds up wound healing after surgical procedures
- Supplements and enhances periodontal surgical treatment
- Reduces scar tissue
- Activates bone regeneration material to accelerate osteogenesis and prevents displacement of the granules
- Optimizes procedures for ridge/socket preservation
PERISOLV - BIOFILM ERASER
PERISOLV® is a new cleaning gel, which is used in addition to mechanical debridement. It is a two component system mixed before clinical application.
- Elimination of the biofilm
- Improved mucositis treatment
- Reduction of pocket depth even in persistent pockets
CLEAN&SEAL - VIDEO:
1. Jepsen S et al. Primary prevention of periimplantitis: managing periimplant mucositis. J Clin Periodontol 2015; 42(Suppl. 16):
S152-S157. doi: 10.1111/jcpe.12369.
2. Costa FO et al. Peri-implant disease in subjects with and without preventive maintenance: a 5-year follow-up. J Clin Periodontol
2012; 39(2): 173-183. doi: 10.1111/j.1600-051X.2011.01819.x.
3. Heitz-Mayfield LJ, Salvi GE ‘Peri-implant mucositis’ J Periodontol. 2018 Jun;89 Suppl 1:S257-S266. doi: 10.1002/JPER.16-0488.
4. Berglundh T, Armitage G, et al. Peri-implant diseases and conditions: Consensus report of workgroup 4 of the 2017 World Workshop on the Classification of Periodontal and Peri-Implant Diseases and Conditions. J Periodontol. 2018;89(Suppl 1): S313–S318.
5. Jurczyk K, Nietzsche S, Ender C, Sculean A, Eick S ‘In-vitro activity of sodium-hypochlorite gel on bacteria associated with periodontitis’ Clin Oral Investig. 2016 Nov;20(8):2165-2173. Epub 2016 Jan 12
6. Pirnazar P, Wolinsky L, Nachnani S, Haake S, Pilloni A, Bernard GW. ‘Bacteriostatic effects of hyaluronic acid.’ J Periodontol 1999;70:370–4.
7. Engstrom PE, Shi XQ, Tronje G, Larsson A, Welander U, Frithiof L, Engstrom GN (2001) The effect of hyaluronan on bone and soft tissue and immune response in wound healing. J Periodontol 72: 1192–1200. doi:10.1902/jop.2000.72.9.1192
8. Asparuhova M, Kiryak D, Eliezer M, Mihov D, Sculean A. ‘Activity of two hyaluronan preparations on primary human oral fibroblasts’ . J Periodontal Res 2018 Sep 27. Epub 2018 Sep 2
9. Longaker T et al. ‘Studies in Fetal Wound Healing: V. A prolonged presence of hyaluronic acid characterizes fetal wound healing’ Ann. Surg. 1991; April:292–296.
10. Mast BA et al. ‘Hyaluronic Acid Modulates Proliferation, Collagen and Protein Synthesis of Cultured Fetal Fibroblast’ Matrix, 1993;13:441–44