Clean & Seal
A new non-surgical concept for mucositis treatment. Efficient, simple and biocompatible - now available at Unident!
The CLEAN&SEAL® concept, which was developed based on scientific data1, 2 provides guidance and support for the treatment and control of peri-implant mucositis. It allows clinicians to save implants and prevent the development of peri-implantitis, which helps to further prevent larger procedures required to rebuild peri-implant tissue.
Clinical Case with Clean and Seal Concept
Mandibular Suprabony Defect Case treated with Perisolv and Hyadent BG
Clinical case and insights by Dr Christopher Appelqvist
With Courtesy of Dr Christopher Appelqvist
Provides guidance and support for the treatment and control of peri-implant mucositis
Peri-implant disease is divided into two subgroups: peri-implant mucositis,1-3 which is characterized by soft tissue inflammation without bone loss and peri-implantitis, which is characterized by progressive loss of the supporting bone.4 If left untreated, in the worst-case peri-implantitis can result in the loss of the affected implant. This problem is relatively new to clinicians and dissatisfying for patients. It is of great importance to treat peri-implant disease at an early stage, with infection control and extensive debridement being crucial for positive treatment outcomes.1, 2 The likelihood of success is further increased by the supportive application of sealing agents for protection and regenerative support and by regular follow-up to monitor and control inflammation.6
EARLY AND EFFECTIVE INTERCEPTION OF PERI-IMPLANT DISEASE
PROVIDED BY DR MARISA RONCATI (ITALY)
Effects of Clean & Seal
1. ATTRACTS BLOOD
2. STABILIZES COAGULUM AND SUPPORTS TISSUE REGENERATION
3. BACTERIOSTATIC EFFECT PROVIDES PROTECTION
4. GROWTH FACTORS ATTRACTED BY HYALURONIC ACID
5. COORDINATES INFLAMMATION AND ACCELERATES ANGIOGENESIS
• SOFTENING OF THE EXTRACELLULAR MATRIX OF THE BIOFILM5
• ENHANCING BACTERIAL REMOVAL BY MECHANICAL DEBRIDEMENT
• ELIMINATION OF THE BIOFILM
HYADENT - TISSUE REGENERATOR
Each pack of HYADENT BG contains two cartridges, each filled with 1.2 ml of hyaluronic acid at a concentration of 1.8% (1.6% cross-linked, 0.2% natural hyaluronic acid). One cartridge contains sufficient hyalu-ronic acid for multiple application according to the proposed protocol.
- Speeds up wound healing after surgical procedures
- Supplements and enhances periodontal surgical treatment
- Reduces scar tissue
- Activates bone regeneration material to accelerate osteogenesis and prevents displacement of the granules
- Optimizes procedures for ridge/socket preservation
PERISOLV - BIOFILM ERASER
PERISOLV® is a new cleaning gel, which is used in addition to mechanical debridement. It is a two component system mixed before clinical application.
- Elimination of the biofilm
- Improved mucositis treatment
- Reduction of pocket depth even in persistent pockets
CLEAN&SEAL - VIDEO:
1. Jepsen S et al. Primary prevention of periimplantitis: managing periimplant mucositis. J Clin Periodontol 2015; 42(Suppl. 16):
S152-S157. doi: 10.1111/jcpe.12369.
2. Costa FO et al. Peri-implant disease in subjects with and without preventive maintenance: a 5-year follow-up. J Clin Periodontol
2012; 39(2): 173-183. doi: 10.1111/j.1600-051X.2011.01819.x.
3. Heitz-Mayfield LJ, Salvi GE ‘Peri-implant mucositis’ J Periodontol. 2018 Jun;89 Suppl 1:S257-S266. doi: 10.1002/JPER.16-0488.
4. Berglundh T, Armitage G, et al. Peri-implant diseases and conditions: Consensus report of workgroup 4 of the 2017 World Workshop on the Classification of Periodontal and Peri-Implant Diseases and Conditions. J Periodontol. 2018;89(Suppl 1): S313–S318.
5. Jurczyk K, Nietzsche S, Ender C, Sculean A, Eick S ‘In-vitro activity of sodium-hypochlorite gel on bacteria associated with periodontitis’ Clin Oral Investig. 2016 Nov;20(8):2165-2173. Epub 2016 Jan 12
6. Pirnazar P, Wolinsky L, Nachnani S, Haake S, Pilloni A, Bernard GW. ‘Bacteriostatic effects of hyaluronic acid.’ J Periodontol 1999;70:370–4.
7. Engstrom PE, Shi XQ, Tronje G, Larsson A, Welander U, Frithiof L, Engstrom GN (2001) The effect of hyaluronan on bone and soft tissue and immune response in wound healing. J Periodontol 72: 1192–1200. doi:10.1902/jop.2000.72.9.1192
8. Asparuhova M, Kiryak D, Eliezer M, Mihov D, Sculean A. ‘Activity of two hyaluronan preparations on primary human oral fibroblasts’ . J Periodontal Res 2018 Sep 27. Epub 2018 Sep 2
9. Longaker T et al. ‘Studies in Fetal Wound Healing: V. A prolonged presence of hyaluronic acid characterizes fetal wound healing’ Ann. Surg. 1991; April:292–296.
10. Mast BA et al. ‘Hyaluronic Acid Modulates Proliferation, Collagen and Protein Synthesis of Cultured Fetal Fibroblast’ Matrix, 1993;13:441–44